Well, with a title like that, it has to be a zombie game!
Made by the Flying Frog (which also made A Touch of Evil, above), once again we have a board game where players control different characters and play different missions, this time on a somewhat randomized board. Unlike A Touch of Evil, Last Night on Earth is always played competitively. There are always 4 Hero Characters, and one (or two) players commands the horde of zombies that try to kill the characters.
The typical mission is to kill 15 zombies in 15 turns, or you run out of daylight and the zombies automatically win. The zombies also win if they kill at least two of the four characters, that's it. The characters are resourceful with ranged weapons and specail abiltiies, able to take multiple hits and trade items amongst each other. The zombies, well... they outnumber you, move slower but surround you with mob tactics, and the zombie player is always drawing cards used to give bonuses to combat or play events. The players only draw a card (like to get a weapon) when they search inside a building. So the zombie player seems to be at a huge advantage, so the players HAVE to work together to survive, like holeing up in the same building, using baiting or hit-and-run tactics, etc. There are 4 other kinds of missions as well. There is also an expansion set that I haven't bought.
Problem is, some of the gamers that I play with, especially the wife, DO NOT like competitive play. Playing nice in this game will quickly give the game away. If all players play without holding back, the game is usually close at the end. The point is, with intelligent people working with and against you, you're usually going to have a challenge.
This game doesn't have near the countless counters and game pieces that A Touc of Evil has. There a 8 character and 5 different missions. 6 L-shaped boards go around a central, double-sided square (you use 4 of the 6 in a game), which have the town buildings on them. So like Settlers, the boad is different every time!
The game's website:
http://www.flyingfrog.net/lastnightonearth/